Research Article

Nutritional Preconditioning of Apigenin Alleviates Myocardial Ischemia/Reperfusion Injury via the Mitochondrial Pathway Mediated by Notch1/Hes1

Table 1

Api preserved reduced the levels of lipid peroxidation, the activities of antioxidant enzymes, and the ferric reducing antioxidant power in the myocardium against SI/R injury.

GroupsMDA content (nmol/g tissue)CAT activity (U/g tissue)SOD activity (U/g tissue)GPx activity (U/g tissue)FRAP (mmol Fe2+/L)

Control31.6 ± 2.315.5 ± 1.285.1 ± 4.523.1 ± 1.55.29 ± 0.26
SI/Raaaaa
Api + SI/Rbbbbb
Api + SI/R + GSI
SI/R + GSI

Values are presented as of five individual experiments. (a) vs. control group; (b) vs. SI/R group.