High Concentration of Low-Density Lipoprotein Results in Disturbances in Mitochondrial Transcription and Functionality in Endothelial Cells

Figure 5

High LDL increases mtDNA content. Human primary endothelial cells were cultured in standard medium (con) or medium containing 1 mg/ml LDL (high LDL) for 7 days. Total DNA was isolated, and mtDNA content was measured by semiquantitative real-time PCR using NXN as nuclear reference gene. Data are ; ; vs. con.