Table 3: Differential gene expression of mitochondrial transcripts after high LDL treatment. Comparison of the expression of mitochondrial protein coding genes and ribosomal RNAs between untreated cells and cells treated with high LDL. The L2FC (log 2-fold change) states the average difference in gene expression between both treatments. Positive L2FC values denote upregulation by high LDL; negative values denote downregulation. A Wald test from DESeq2 was used to calculate the significance of the change in the expression. The adjusted values take the number of tested genes into account.

Gene nameEnsembl gene IDL2FC valueAdjusted value

MT-RNR1ENSG000002114591.86
MT-RNR2ENSG000002100821.52
MT-ND6ENSG000001986951.67
MT-ND1ENSG000001988881.34
MT-ND4ENSG000001988861.29
MT-ND3ENSG000001988401.33
MT-CO1ENSG000001988041.34
MT-CO2ENSG000001987121.19
MT-ATP6ENSG000001988991.00
MT-CYBENSG000001987271.01
MT-ND2ENSG000001987630.90
MT-CO3ENSG000001989380.87
MT-ND4LENSG000002129071.04
MT-ND5ENSG000001987861.40
MT-ATP8ENSG000002282530.82