Review Article
Proresolving Lipid Mediators: Endogenous Modulators of Oxidative Stress
Table 2
Main endogenous enzymatic and nonenzymatic antioxidant systems.
| Antioxidant | Function | Localization |
| SOD | Removal of ·O2- | Mitochondria | Catalase | Dismutation of H2O2 | Peroxisomes | Glutathione peroxidase | Removal of H2O2 | Cytoplasm | Glutathione reductase | Reduction of glutathione | Cytoplasm | Peroxiredoxin | Removal of H2O2, ONOO-, hydroperoxides | Cytoplasm, plasma membrane | Transferrin/ferritin/ lactoferrin/ceruloplasmin | Scavenging of transition metals | Plasma and cytoplasm | Glutathione | Scavenging of reactive species | Ubiquitous | Uric acid | Scavenging of reactive species | Ubiquitous | Pyruvate | Scavenging of reactive species | Ubiquitous | Amino acids | Scavenging of reactive species | Ubiquitous |
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