Research Article
Ginkgo Biloba Leaf Extract Attenuates Atherosclerosis in Streptozotocin-Induced Diabetic ApoE-/- Mice by Inhibiting Endoplasmic Reticulum Stress via Restoration of Autophagy through the mTOR Signaling Pathway
Figure 12
Effects of GBE on endoplasmic reticulum stress hallmark expressions in the aortas of mice. The expressions of p-JNK, CHOP, and Caspase-12 were determined by Western blotting. (a, b) The expression of p-JNK ( in each group); (c, d) the expression of CHOP ( in each group); (e, f) the expression of Caspase-12 ( in each group). and , compared to the model group. (1) Normal group, (2) model group, (3) model control group, (4) atorvastatin group, (5) rapamycin group, (6) 200 mg/kg/day GBE group, and (7) 400 mg/kg/day GBE group.
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