Oxidative Medicine and Cellular Longevity / 2019 / Article / Fig 5

Research Article

Modulations of Histone Deacetylase 2 Offer a Protective Effect through the Mitochondrial Apoptosis Pathway in Acute Liver Failure

Figure 5

CAY10683 could alleviate the hepatic pathology and liver function in ALF rats. (a) HE staining was used to detect pathological changes in liver tissue. (b, f) Tunnel staining was used to detect the apoptotic index in liver tissue. (c) The ultrastructure of liver tissue and the mitochondrial membranes were detected by electron microscopy. (d-f) The rat serum ALT, AST, and TBIL levels were detected by the fully automated Aeroset chemistry analyzer. , compared with the control group. , compared with the LPS/D-gal-treated model group.

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