Oxidative Medicine and Cellular Longevity / 2019 / Article / Fig 2

Review Article

Dichloroacetate (DCA) and Cancer: An Overview towards Clinical Applications

Figure 2

New drug formulations containing DCA. (a) Schematic representation of Os-DCA and Ru-DCA complexes [81]. (b) Doxorubicin (DOX)-DCA complex [83]. (c) Dual action Pt prodrugs of kiteplatin and DCA [84]. (d) Examples of triple action Pt(IV) derivatives of cisplatin containing DCA (red), derivatives of cisplatin (black), and COX inhibitors (green) [85]. (e) Chemical structure of DPB containing DCA (red), biotin (blue), and Platinum (Pt) complex (black) [86].

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