Research Article
Melatonin Reduces Androgen Production and Upregulates Heme Oxygenase-1 Expression in Granulosa Cells from PCOS Patients with Hypoestrogenia and Hyperandrogenia
Figure 6
Effect of melatonin on HO-1 expression in GCs. (a) TAC and (b–e) quantitation of SOD1, CAT, GPx, and HO-1 mRNA expression by qPCR. (f) Nrf2 and p-Nrf2 translation; the WB is a representative image of an experiment. (g) GSH, (h) SOD, and (i) HO-1 concentrations. (j) HO-1 expression in melatonin or ML385-treated PCOS GCs. in each experiment. Data are shown as . Different superscript letters (A–C) in each column represent statistically significant differences between different groups ().
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