Research Article

Evidence of Blood and Muscle Redox Status Imbalance in Experimentally Induced Renal Insufficiency in a Rabbit Model

Table 2

Blood redox status indices in the control and uremic groups.

BloodControl group ()95% confidence intervalUremic group ()95% confidence interval
Lower boundUpper boundLower boundUpper bound

Uric acid (mg/dl)0.9071.8861.182.670.263
GSH (μmol/g protein)10.44814.41214.1220.880.033
GSSG (μmol/g protein)0.0160.0390.0280.0670.110
Ratio (GSH/GSSG)376.357585.642305.36545.210.511
GR (U/g protein)127.393225.423122.04184.150.425
TAC (μmol DPPH/ml)0.7190.8520.6790.8380.611
CAT (U/mg protein)307.35376.68273.01334.260.131
PC (nmol/mg protein)0.4270.7800.4910.7480.888
TBARS (nmol/ml)4.2925.9485.448.620.060

Data are presented as . The exact statistical significance value and the 95% confidence intervals are reported. GSH: reduced glutathione; GSSG: oxidized glutathione; TAC: total antioxidant capacity; CAT: catalase; PC: protein carbonyls; TBARS: thiobarbituric acid reactive substances, statistical significance between the control and uremic groups, .