Green Tea Extract Ameliorates Ischemia-Induced Retinal Ganglion Cell Degeneration in Rats

<div>Apoptosis analysis of retinal ganglion cells after the green tea extract treatment effect on normal and ischemia-injured rats. Retinal ganglion cell (RGC) apoptosis was evaluated by the TUNEL analysis on retinal sections on day 7 after ischemic reperfusion (IR) injury in (a) the saline-fed normal rats, (b) green tea extract- (GTE-) fed normal rats, (c) saline-fed rats with ischemic injury, and (d) GTE-fed rats with ischemic injury. ONL: outer nuclear layer; INL: inner nuclear layer; GCL: ganglion cell layer (on the white-dotted line); green: TUNEL (apoptotic cells); blue: DAPI (nucleus). (e) Quantitative analysis of TUNEL-positive cells in the GCL. 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Oxidative Medicine and Cellular Longevity

fig5

Figure 5

Figure 5: Green Tea Extract Ameliorates Ischemia-Induced Retinal Ganglion Cell Degeneration in Rats 