Sailuotong Capsule Prevents the Cerebral Ischaemia-Induced Neuroinflammation and Impairment of Recognition Memory through Inhibition of LCN2 Expression

Figure 1

SLT treatment reduced ischaemic infarct volume in the cerebral ischaemia model. (a) Timeline depicts the treatment of SLT and assessments of the cognitive functions of rats. The male rats () were orally treated with SLT at a daily dose of 16.5 mg/kg and 33 mg/kg for 4 weeks. After surgery for 22 days, memory tests were conducted. The training trial was performed four times a day for 5 days. (b) Cerebral infarct volume was assessed via TTC staining 24 h after cerebral ischaemia. Neurological score (c) of rats after cerebral ischaemia was assessed using a five-point scale system. Data are expressed as the (). vs. sham group; ^#, ^##, and ^### vs. the model groups.

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