Markers of Oxidant-Antioxidant Equilibrium in Patients with Sudden Sensorineural Hearing Loss Treated with Hyperbaric Oxygen Therapy

Table 1

Markers of oxidative stress in the blood of healthy members of the control group and patients with sudden sensorineural hearing loss (SSNHL) treated with hyperbaric oxygen (HBO) therapy and the values of haemoglobin concentration and haematocrit in the SSNHL patients.

Parameters	Control	SSNHL patients
		Before HBO therapy	~5 min after first HBO session	After 14 HBO sessions
TBARS in plasma (nmol MDA/mL)
TBARS in erythr. (nmol MDA/g Hb)				27.06 ± 8.39^++
CAT (10^4 IU/g Hb)			62.93 ± 8.23^+++
SOD (U/g Hb)				713.26 ± 72.89^+++^†
GPx (U/g Hb)				9.61 ± 4.75^+++
HGB (g/mL)				14.64 ± 1.43
HCT (%)				41.29 ± 3.60

TBARS: thiobarbituric acid reactive substances; CAT: catalase; GPx: glutathione peroxidase; SOD: superoxide dismutase; HGB: haemoglobin; HCT: haematocrit. The values are expressed as deviations (SD) of the means. ⁺Statistically significant difference compared to the control group (⁺; ⁺⁺; ⁺⁺⁺). Statistically significant difference compared to parameters measured before the HBO therapy (; ). ^†Statistically significant difference compared to the parameters measured after the 1st HBO session (^†).