Review Article
Targeting Early Atherosclerosis: A Focus on Oxidative Stress and Inflammation
Figure 4
Prothrombotic, proatherogenic, and inflammatory effects of platelet activation. The platelet-endothelium interaction triggers platelet activation, considered as a critical point in all phases of atherosclerosis. ECM: extracellular matrix; MMP-2: matrix metalloproteinases 2; MMP-9: matrix metalloproteinases 9; PF4: platelet factor 4; SDF-1: stromal cell-derived factor-1.