Ferritinophagic Flux Activation in CT26 Cells Contributed to EMT Inhibition Induced by a Novel Iron Chelator, DpdtpA

Figure 1

DpdtpA-induced growth inhibition involved ROS generation. (a) Structure of DpdtpA; (b) antiproliferative effect of DpdtpA on the CT26 cells; (c) DpdtpA induced ROS production: C1, 0.7% DMSO; C2, 0.78 μM DpdtpA; C3, 0.78 μM DpdtpA+NAC (1.5 mM). The data from MTT were from five measurements, and ROS assays were conducted twice.

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