Metformin Protects against Oxidative Stress Injury Induced by Ischemia/Reperfusion via Regulation of the lncRNA-H19/miR-148a-3p/Rock2 Axis

Figure 2

Effect of metformin on the levels of oxidative stress. (a) Activities of SOD in the serum and the brain. (b) Levels of MDA in the serum and the brain. (c) Levels of NO in the serum and the brain. (d) Activities of GSHPx in the serum and the brain. Data were expressed as the ( per group). and versus the vehicle group by 1-way analysis of variance with Tukey’s multiple comparison test. ^# and ^## versus the sham group by 1-way analysis of variance with Tukey’s multiple comparison test.

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