Research Article
Betulinic Acid Suppresses Breast Cancer Metastasis by Targeting GRP78-Mediated Glycolysis and ER Stress Apoptotic Pathway
Figure 5
BA inhibits breast cancer lung colonization in vivo. (a) Bioluminescent imaging indicated that BA significantly reduced breast cancer cell lung colonization compared with vehicle-treated controls. (b) Logarithmic value of luminescent intensity after treatment with vehicle or BA (values represented as the , , ). (c) Hematoxylin and eosin staining demonstrated the reduction of lung metastatic lesions in BA-treated mice (the scale bars indicate 100 μm).
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