Figure 1: Variation in nutrient intake and body weight of LDLr-/- mice after treatment with guarana soft drinks (normal and zero) for 8 consecutive weeks. (a) GSD mice consumed less food on average daily than control or Z-GSD-fed mice during 8 consecutive weeks (). (b) On the other hand, the GSD group presented polydipsia compared to the control () and Z-GSD groups (#). (c) There were no differences in caloric intake between groups. (d) During this period, transient changes in body weight in response to GSD or Z-GSD intake were not observed (two-way ANOVA with repeated measures).