Research Article
Classic Prescription, Kai-Xin-San, Ameliorates Alzheimer’s Disease as an Effective Multitarget Treatment: From Neurotransmitter to Protein Signaling Pathway
Figure 7
KXS treatment inhibited oxidative stress and neuroinflammation-induced apoptosis in vitro. KXS treatment decreases the levels of ROS (a) and MMP (b), the concentration of IL-1β and TNF-α (c and d), and the expressions of Bax/bcl-2 and cleaved-caspase-3 (e and f), and the cell apoptosis rate (g and h) enhanced by Aβ25-35 in PC12 cells. Values were the (). , , and vs. the control group; #, ##, and ###vs. the Aβ group; and &, &&, and &&&vs. the LY+KXS group.
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