Tocotrienol-Rich Fraction (TRF) Treatment Promotes Proliferation Capacity of Stress-Induced Premature Senescence Myoblasts and Modulates the Renewal of Satellite Cells: Microarray Analysis

Table 2

GSEA analysis on the biological processes regulated by the stress-induced premature senescence as compared to the untreated young control ().

GO accession	Biological process	NES	value
GO:0006576	Cellular biogenic amine metabolic process	1.33	2.63E − 02
GO:0044106	Cellular amine metabolic process	1.33	2.63E − 02
GO:0046885	Regulation of hormone biosynthetic process	−1.40	3.17E − 02
GO:0051004	Regulation of lipoprotein lipase activity	−1.32	3.28E − 02
GO:0070874	Negative regulation of glycogen metabolic process	−1.44	3.39E − 02
GO:0032106	Positive regulation of response to extracellular stimulus	−1.48	3.45E − 02
GO:0032109	Positive regulation of response to nutrient levels	−1.48	3.45E − 02
GO:0031442	Positive regulation of mRNA 3′-end processing	−1.24	3.57E − 02
GO:0043001	Golgi to plasma membrane protein transport	−1.41	3.64E − 02
GO:2000973	Regulation of pro-B cell differentiation	−1.69	3.77E − 02
GO:0032494	Response to peptidoglycan	1.40	3.85E − 02
GO:0006400	tRNA modification	1.50	3.92E − 02
GO:0045807	Positive regulation of endocytosis	−1.34	4.11E − 02
GO:0006970	Response to osmotic stress	−1.15	4.17E − 02
GO:0090199	Regulation of release of cytochrome c from mitochondria	1.29	4.35E − 02
GO:0042953	Lipoprotein transport	−1.18	4.35E − 02
GO:0044872	Lipoprotein localization	−1.18	4.35E − 02
GO:0061418	Regulation of transcription from RNA polymerase II promoter in response to hypoxia	−1.52	4.35E − 02
GO:0048644	Muscle organ morphogenesis	−1.70	4.35E − 02
GO:0022615	Protein to membrane docking	−1.49	4.41E − 02
GO:0035563	Positive regulation of chromatin binding	1.55	4.44E − 02
GO:0048259	Regulation of receptor-mediated endocytosis	−1.25	4.48E − 02
GO:0032922	Circadian regulation of gene expression	−1.25	4.55E − 02
GO:0006694	Steroid biosynthetic process	−1.37	4.55E − 02
GO:2001014	Regulation of skeletal muscle cell differentiation	−1.57	4.55E − 02
GO:2000641	Regulation of early endosome to late endosome transport	−1.31	4.62E − 02
GO:0043112	Receptor metabolic process	−1.25	4.69E − 02
GO:0006891	Intra-Golgi vesicle-mediated transport	−1.38	4.69E − 02
GO:0035330	Regulation of hippo signalling	−1.44	4.69E − 02
GO:0035640	Exploration behavior	−1.47	4.69E − 02
GO:0006270	DNA replication initiation	1.46	4.76E − 02
GO:0031536	Positive regulation of exit from mitosis	1.29	4.76E − 02
GO:0048020	CCR chemokine receptor binding	−1.41	4.76E − 02
GO:0017144	Drug metabolic process	−1.42	4.76E − 02
GO:2000095	Regulation of Wnt signalling pathway, planar cell polarity pathway	−1.69	4.76E − 02
GO:0042347	Negative regulation of NF-kappaB import into nucleus	−1.37	4.84E − 02
GO:0046854	Phosphatidylinositol phosphorylation	−1.38	4.84E − 02
GO:0006901	Vesicle coating	−1.42	4.84E − 02
GO:0051045	Negative regulation of membrane protein ectodomain proteolysis	1.62	4.88E − 02
GO:0006335	DNA replication-dependent nucleosome assembly	1.51	4.88E − 02
GO:0034723	DNA replication-dependent nucleosome organization	1.51	4.88E − 02
GO:2000649	Regulation of sodium ion transmembrane transporter activity	−1.33	4.92E − 02
GO:0048260	Positive regulation of receptor-mediated endocytosis	−1.35	4.92E − 02
GO:0002381	Immunoglobulin production involved in immunoglobulin-mediated immune response	−1.36	4.92E − 02
GO:0018879	Biphenyl metabolic process	−1.45	4.92E − 02