Recombinant Klotho Protects Human Periodontal Ligament Stem Cells by Regulating Mitochondrial Function and the Antioxidant System during H<sub>2</sub>O<sub>2</sub>-Induced Oxidative Stress

<div>Klotho administration ameliorated H<sub>2</sub>O<sub>2</sub>-induced apoptosis in hPDLSCs. (a) Flow cytometric analysis of groups with different treatments and the percentage of Annexin V/7-AAD positive cells. (b) The expression of c-Caspase-3 in hPDLSCs with different treatments was detected by immunofluorescence staining. Scale bars: 50 <i>μ</i>m. 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Oxidative Medicine and Cellular Longevity

fig3

Figure 3

Figure 3: Recombinant Klotho Protects Human Periodontal Ligament Stem Cells by Regulating Mitochondrial Function and the Antioxidant System during H<sub>2</sub>O<sub>2</sub>-Induced Oxidative Stress 

Figure 3 | Recombinant Klotho Protects Human Periodontal Ligament Stem Cells by Regulating Mitochondrial Function and the Antioxidant System during H2O2-Induced Oxidative Stress 