The Research Progress of Host Genes and Tuberculosis Susceptibility

Table 1

Summary of association between HLA genes and TB susceptibility.

HLA	Region	HLA antigen allele	Relationship with TB	References
HLA-I gene	Canada	B8	Susceptible	[6]
	India	A2	Susceptible	[7]
		B18	Antagonized	[7]
	Italy	A2, B14	Antagonized	[8]
	Iran	A26, B27	Antagonized	[9]
		B17	Susceptible	[9]
	China	B27, B35	Susceptible	[10]
		A31	Antagonized	[10]
HLA-II gene	Govinda	DRB11302, DQB10301-0304	Susceptible	[11]
	Cambodia	DQ β57, DQB10301, -0303, DQB104 (-0401, -0402), DQB10503, DQB10601, -0602, -0603	Susceptible	[12]
	Iran	DRBI07, DQA10101	Susceptible	[13]
	Xiangxi, China	DRB109	Susceptible	[14, 15]
		DRB111	Antagonized
	Xinjiang, China	DRB112	Susceptible	[14, 15]
		DRB111	Antagonized
	Russia	DRB113	Susceptible	[16]
	India	DQB10503, -0502, DR2, DQB10601, DQ1, DRB11501 (DR2), DRB11501-DRB50101-DQA10103-DQB10601	Susceptible	[4, 17, 18]
		DRW6	Antagonized	[19]
	Poland	DRB116, DQB105, DRB11601-DQB10502, DRB104-DQB103, DRB114-DQB105	Susceptible	[20, 21]
		DRB113	Antagonized	[20]