Activators and Inhibitors of NRF2: A Review of Their Potential for Clinical Development

Table 2

Selected peptides acting as NRF2-KEAP1 protein-protein interaction inhibitors.

Sequence	Mechanism of action	Reference
LDEETGEFL-NH2	Binding to KEAP1-Kelch domain	[100, 101]
DEETGE-CAL-Tat (NH2-RKKRRQRRR-PLFAERLDEETGEFLPNH2)		[103]
Ac-DPETGEL-OH		[102]
FITCβ-DEETGEF-OH		[102]
FITC-β-LDEETGEFL-OH		[102]
Ac-DEETGEF-OH		[102]
Ac-DPETGEL-OH		[102]
FITC-LDEETGEFL-NH2		[100]
FAM-LDEETGEFL-NH2		[108]
LQLDEETGEFLPIQGK(MR121)-OH		[107]
Ac-LDEETGEFL-NH2		[100, 101]
Ac-DPETGEL-NH2		[104]
Ac-NPETGEL-OH		[104]
St-DPETGEL-OH		[104]
YGRKKRRQRRRLQLDEETGEFLPIQ		[162]
c[GQLDPETGEFL]		[105]