Research Article

Ethyl Acetate Fraction of Lannea microcarpa Engl. and K. Krause (Anacardiaceae) Trunk Barks Corrects Angiotensin II-Induced Hypertension and Endothelial Dysfunction in Mice

Figure 6

Effect of LMAE on CaCl2-induced contraction ex vivo. Cumulative concentrations of CaCl2 (10-5-10-2 M) were added to aortic rings with intact (a) or denuded (b) endothelium in Ca2+-free Krebs solution, containing 80 mM KCl, to activate voltage-dependent calcium channels (VDCCs). Aortic rings were either preincubated without vehicle (0.02% of DMSO) or LMAE (500 μg/mL). The results are expressed as . (). .
(a)
(b)