Research Article
Mechanisms of Anthracycline-Enhanced Reactive Oxygen Metabolism in Tumor Cells
Table 3
Effect of anthracycline antibiotics on superoxide production by the tumor microsomal fraction. Superoxide production in tumor microsomes was determined as described in Table 2. For these studies, all drugs were present at a concentration of 135 μM.
| ||||||||||||||||
a.; number in parentheses is number of experiments performed; bsignificantly higher than the control rate of superoxide formation in tumor microsomes (; Table 2). |