Indigo Naturalis Suppresses Colonic Oxidative Stress and Th1/Th17 Responses of DSS-Induced Colitis in Mice

Figure 1

Effects of QD on body loss (a), DAI (b), colon length (c), and histopathological changes (d, e) of mice with DSS-induced colitis. Colitis was induced in all groups except the control group. QD and SASP were administered to mice from days 6 to 12. The change in body weight was taken as the difference between the body weight before the induction of colitis and that immediately before sacrifice on day 13. The DAI was determined by combining the scores for (1) body weight loss, (2) stool consistency, and (3) stool blood. On day 13, the mice were sacrificed, their colon length was measured, and the colonic tissue damage was evaluated by histopathological analysis (H&E staining). Data were expressed as (). ^###, compared with the control group; , , and , compared with the DSS model group.

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