Research Article

Nicotinic Agonist Inhibits Cardiomyocyte Apoptosis in CVB3-Induced Myocarditis via α3β4-nAChR/PI3K/Akt-Dependent Survivin Upregulation

Figure 3

The mRNA expression of CVB3 in NRC and H9c2 cells after treatment with different concentrations of nicotine. After being infected by CVB3 for 2 h, the culture medium was removed and different concentrations of freshly dissolved nicotine were added to stimulate nAChRs. Total mRNA was collected 36 h later for the evaluation of CVB3 mRNA by RT-qPCR. and vs. the control group.