Nerolidol Suppresses the Inflammatory Response during Lipopolysaccharide-Induced Acute Lung Injury via the Modulation of Antioxidant Enzymes and the AMPK/Nrf-2/HO-1 Pathway
Nerolidol protects against LPS-induced alveolar-capillary barrier disruption and leukocyte infiltration. (a) Alveolar-capillary barrier disruption was determined by protein leakage via a Bradford protein assay. (b) Leukocyte infiltration was determined by MPO activity in BALF. Values are expressed as of 3-4 mice per group. # represents a significant difference between the indicated group and the control group; represents a significant difference between the indicated group and the LPS groups.