Cerebroprotective Effect against Cerebral Ischemia of the Combined Extract of Oryza sativa and Anethum graveolens in Metabolic Syndrome Rats

Figure 12

Effect of various doses of OA extract on histopathological appearance of common carotid artery. (a) Light microscope of common carotid artery stained with H&E at 40x magnification. (b) Tunica media thickness in the common carotid artery. Data are presented as (/group). ^AAA; compared to naïve intact rats, ^BB; compared to sham operation which received HCHF diet and vehicle and , 0.01, 0.001, respectively; compared to MCAO rats which received HCHF and vehicle. HCHF: high-carbohydrate high-fat diet; MCAO: right middle cerebral artery occlusion; OA1, OA2, and OA3: the combined extract of O. sativa and A. graveolens at doses of 0.5, 5, and 50 mg/kg BW, respectively.

(a)

(b)