Cerebroprotective Effect against Cerebral Ischemia of the Combined Extract of Oryza sativa and Anethum graveolens in Metabolic Syndrome Rats

Figure 9

Effect of various doses of OA extract on the expression of vascular cell adhesion molecule 1 (VCAM-1) in common carotid artery. (a) Representative western blot showing the levels of VCAM-1. (b) Relative density of VCAM-1. Data are presented as (/group). ^AAA; compared to naïve intact rats, ^BBB; compared to sham operation which received HCHF diet and vehicle and , 0.01, and 0.001, respectively; compared to MCAO rats which received HCHF and vehicle. HCHF: high-carbohydrate high-fat diet; MCAO: right middle cerebral artery occlusion; OA1, OA2, and OA3: the combined extract of O. sativa and A. graveolens at doses of 0.5, 5, and 50 mg/kg BW, respectively.

(a)

(b)