miR-25 Promotes Cell Proliferation, Migration, and Invasion of Non-Small-Cell Lung Cancer by Targeting the LATS2/YAP Signaling Pathway

Figure 2

Overexpression or inhibition of miR-25 on cell proliferation, migration, and invasion in both A549 and H1299 cells. (a, b) Colony formation of cells transfected with the miR-25 precursor or the miR-25 inhibitor or with respective controls. (c, d) Wound healing assays for cell migration with altered miR-25 expression. (e, f) Transwell assays for cell invasion with altered miR-25 expression. (g) Western blot analyses of the expression of metastasis-related proteins, E-cadherin, Vimentin, and MMP9 in A549 and H1299 cells with altered miR-25 expression. Results were presented as of three independent experiments. , , and .

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