Research Article
Melanogenic Effects of Maclurin Are Mediated through the Activation of cAMP/PKA/CREB and p38 MAPK/CREB Signaling Pathways
Figure 2
Maclurin activated the cAMP-PKA-CREB pathway. (a) cAMP production assay and (b) ELISA were performed to analyze PKA activity. (c) The CREB phosphorylation levels were measured using an ELISA kit and confirmed by (d) a Western blot analysis. vs. control group, o vs. maclurin (50 μM)-treated control. M: maclurin; Fk: forskolin.
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