Hyperglycemia-Induced Oxidative Stress Abrogates Remifentanil Preconditioning-Mediated Cardioprotection in Diabetic Rats by Impairing Caveolin-3-Modulated PI3K/Akt and JAK2/STAT3 Signaling

Table 1

General characteristics of diabetic rats at the end of the treatment period.

	C	D	D+NAC
Water intake (mL/kg/day)			^,#
Food consumption (g/kg/day)			^,#
Body weight (g)			^,#
Plasma glucose (mM)
Plasma insulin (mU/L)
Plasma triglycerides (mM)			^,#

Control (C) or STZ-induced diabetic (D) rats were treated with or without N-acetylcysteine (1.5 g/kg/day, D+NAC) by oral gavage for four weeks. All the results are expressed as , . Differences in general characteristics were determined by one-way analysis of variance (ANOVA) followed by Tukey’s test. and vs. the C group; vs. the D group.