Zinc Oxide Nanoparticle Synergizes Sorafenib Anticancer Efficacy with Minimizing Its Cytotoxicity

Table 1

Tumor growth inhibition rate and difference in tumor weights. Values are expressed as of 10 animals in each group.

Parameters	SEC	MTX	ZnO-NPs	Sorafenib	ZnO-NPs+sorafenib
Tumor weight (g)		^a	^a	^a	^a	<0.001
Tumor growth inhibition (%)	—	43.72	19.09^b	35.17^c	46.23^c	<0.001

SD: standard deviation; : probability; ; high significance. The test used one-way ANOVA followed by post hoc Tukey. ^aSignificant compared to the control SEC group. ^bSignificant compared to the MTX group. ^cSignificant compared to the ZnO-NP group. ^dSignificant compared to the sorafenib group.