Astragalus membranaceus Injection Suppresses Production of Interleukin-6 by Activating Autophagy through the AMPK-mTOR Pathway in Lipopolysaccharide-Stimulated Macrophages

Figure 6

The AMPK agonist reduced the level of IL-6 in ANA-1 cells. (a) Western blot analysis detecting the activating effect of AICAR on AMPK. β-Actin was used as the control. (b) Western blot analysis of the effect of varying doses of AICAR on the level of IL-6 in ANA-1 cells. β-Actin was used as the control. Data represent (). Asterisks () indicate significant differences compared with the control group (, ). Number signs (#) indicate significant differences compared with the LPS group (^#, ^##).

(a)

(b)