The Recombinant Protein EphB4-Fc Changes the Ti Particle-Mediated Imbalance of OPG/RANKL via EphrinB2/EphB4 Signaling Pathway and Inhibits the Release of Proinflammatory Factors In Vivo

<div>The expression of ephrinB2 is mediated by c-Fos/NFATc1 signaling pathway. (a) Shows that the ephrinB2 gene is regulated by the c-Fos/NFATc1 signaling pathway through sic-Fos RNA and siNFATc1 RNA. We find that it promotes high expression of ephrinB2 gene and protein with Ti (b, c) and the ephrinB2 protein is located on the surface of the BMMs membrane by immunofluorescence. 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Oxidative Medicine and Cellular Longevity

fig3

Figure 3

Figure 3: The Recombinant Protein EphB4-Fc Changes the Ti Particle-Mediated Imbalance of OPG/RANKL via EphrinB2/EphB4 Signaling Pathway and Inhibits the Release of Proinflammatory Factors In Vivo 

Figure 3 | The Recombinant Protein EphB4-Fc Changes the Ti Particle-Mediated Imbalance of OPG/RANKL via EphrinB2/EphB4 Signaling Pathway and Inhibits the Release of Proinflammatory Factors In Vivo 