Hydrogen Sulfide Promotes Cardiomyocyte Proliferation and Heart Regeneration via ROS Scavenging

Figure 6

SOD2 is crucial to CM proliferation under physiological conditions. Primary CMs from P1 mice were treated with siSOD2 and NaHS. (a) Knockdown efficiency of siSOD2. by Student’s -test. (b) Representative images of pH3 and Ki67 immunofluorescence staining. Actinin was used to label CMs, and DAPI was used to label nuclei. Scale . (c–e) Quantification of CM proliferation, as indicated by pH3, Ki67, and Aurora B positive staining. The data are presented as the . ; ns: not significant, by one-way ANOVA with Bonferroni’s multiple comparison test.

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