Research Article

Sinapic Acid Attenuates Cardiovascular Disorders in Rats by Modulating Reactive Oxygen Species and Angiotensin Receptor Expression

Table 6

Linear trend analysis across different investigated groups.

L-NAME+captoprilL-NAME+SAL-NAME+SA+captopril

Cardiac markers
 CK-MB (ng/ml)<0.001
 Troponin I (ng/ml)0.496
Lipid profile
 HDL-C (mg/dl)<0.001
 LDL-C (mg dl)<0.001
 TG (mg/dl)0.008
 Total cholesterol (mg/dl)<0.001
 VLDL-C (mg dl)0.008
Oxidative markers
 GSH (mcg/ml)0.004
 NO synthase 3 (ng/ml)<0.001
 SOD (U mg tissue)<0.001
Vascular markers
 Angiotensin II (pg/ml)0.181
 Angiotensin II receptor 2 (ng/ml)0.005
 Angiopoietin-II (pg/ml)0.014
 Endothelin-1 (pg/ml)0.117

Values are expressed as . : value for the linear trend: L-NAME+captropril < L-NAME+SA < L-NAME+SA+captropril. values ≤ 0.05 were considered significant.