Melatonin Ameliorates MI-Induced Cardiac Remodeling and Apoptosis through a JNK/p53-Dependent Mechanism in Diabetes Mellitus

<div>Effect of melatonin treatment on myocardial TUNEL apoptosis in post-MI diabetic mice. (a) Representative images of TUNEL staining 4 weeks post-MI in diabetic mice. Representative TUNEL staining images are displayed in the upper panel while the images with DAPI staining are displayed in the middle panel demonstrating nuclei of cells. The lower panel exhibits the overlay images to illustrate apoptotic cells. 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Oxidative Medicine and Cellular Longevity

fig3

Figure 3

Figure 3: Melatonin Ameliorates MI-Induced Cardiac Remodeling and Apoptosis through a JNK/p53-Dependent Mechanism in Diabetes Mellitus 