Research Article
Melatonin Ameliorates MI-Induced Cardiac Remodeling and Apoptosis through a JNK/p53-Dependent Mechanism in Diabetes Mellitus
Figure 6
Effect of melatonin and the JNK activator anisomycin on protein levels of apoptotic-related proteins in H9c2 cells challenged by high glucose/high fat under hypoxia. (a) Representative images of western blot of H9c2 cells with or without melatonin and anisomycin treatment. (b) p-JNK to total JNK ratio. (c) p53 level. (d) Bcl-2 level. (e) Bax level. (f) Caspase-3 level. , . vs. CON group, # vs. high-glucose/high-fat treatment under hypoxia, and † vs. HF/HG-hypoxia-MEL group.
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