Oxidative Medicine and Cellular Longevity

Research Article

Salvianolic Acid B Improves Postresuscitation Myocardial and Cerebral Outcomes in a Murine Model of Cardiac Arrest: Involvement of Nrf2 Signaling Pathway

Table 1

Baseline and CA/CPR-related characteristics of mice.


Variables	Vehicle	Sal B	value

Baseline
Body weight (g)			0.257
Body temperature (°C)			0.880
LVP_max (mmHg)			0.943
dp/dt_max (mmHg/s)			0.177
dp/dt_min (mmHg/s)			0.463
Heart rate (bpm)			0.760
Cardiac output (mL/min)			0.101
Resuscitation
Intubation time (s)			0.837
Chest compression rate (beats/min)			0.508
Mean arterial pressure (mmHg)			0.649
Total dose of epinephrine (μg)			0.257
Time to ROSC (s)			0.013^a
ROSC success ( (%))	11 (73%)	13 (86%)	0.648

Values are ; CA: cardiac arrest; CPR: cardiopulmonary resuscitation; Vehicle: mice subjected to CA/CPR treated with normal saline; Sal B: salvianolic acid B; : number of mice; LVP_max: maximum left ventricular pressure; dp/dt_max: maximum rate of developed left ventricular pressure; dp/dt_min: minimum rate of developed left ventricular pressure; bpm: beats per minute; ROSC: return of spontaneous circulation. ^a vs. Vehicle.