IMCA Induces Ferroptosis Mediated by SLC7A11 through the AMPK/mTOR Pathway in Colorectal Cancer

Figure 4

IMCA inhibited the expression of SLC7A11. The relative GSH contents were determined and compared between the IMCA treatment and control groups in DLD-1 (a) and HCT116 (b) cells. Relative mRNA expression of GSS was determined and compared between the IMCA treatment and control groups in DLD-1 (c) and HCT116 (d) cells. Relative protein expression of GSS was determined and compared between the IMCA treatment and control groups in DLD-1 (e) and HCT116 (f) cells. The relative Cys contents were determined and compared between the IMCA treatment and control groups in DLD-1 (g) and HCT116 (h) cells. Relative mRNA expression of SLC7A11 was determined and compared between the IMCA treatment and control groups in DLD-1 (i) and HCT116 (j) cells. Relative protein expression of SLC7A11 was determined and compared between the IMCA treatment and control groups in DLD-1 (k) and HCT116 (l) cells. ; ; .

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