Circulating Levels of CILP2 Are Elevated in Coronary Heart Disease and Associated with Atherosclerosis

Table 1

Clinical characteristics and circulating CILP2 levels of study subjects.

Variable	Controls ()	CHD (7)
Males/female	59/46	98/69	0.587
Age (yr)			0.111
BMI (kg/m^2)			0.704
WHR			< 0.001
SBP (mmHg)			< 0.001
DBP (mmHg)			0.147
TG (mmol/L)	1.22 (0.88,174)	1.31 (0.96,1.98)	0.029
TC (mmol/L)			0.886
HDL-C (mmol/L)			< 0.001
LDL-C (mmol/L)			< 0.05
FFA (μmol/L)	0.53 (0.39,0.69)	0.55 (0.42,0.71)	0.405
FBG (mmol/L)			< 0.001
2 h-BG (mmol/L)			< 0.001
FIns (mU/L)			< 0.001
HbA1c (%)			0.077
HOMA-IR			< 0.001
CILP2 (ng/L)	126.9 (98.0, 141.7)	205.6 (122.0, 411.9)	< 0.001
Gensini score	—	18.0 (11.5-34.0)	< 0.001

BMI: body mass index; SBP: systolic blood pressure; DBP: diastolic blood pressure; WHR: waist-to-hip ratio; FBG: fasting blood glucose; 2 h-BG: 2 h postglucose load blood glucose; FIns: fasting plasma insulin; HOMA-IR: HOMA-insulin resistance index; FFA: free fatty acids; TG: triglyceride; TC: total cholesterol; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; HbA1c: glycosylated hemoglobin; CILP2: cartilage intermediate layer protein 2. Data are or median (interquartile).