Detrimental Effects of UVB on Retinal Pigment Epithelial Cells and Its Role in Age-Related Macular Degeneration

Figure 4

An overview of UVB-induced MAPK/P13K-AKT/p53-mediated cell cycle arrest and cell death in ARPE-19 cells. The cells were irradiated with UVB, and the changes in protein expression in each pathway illustrated were studied using inhibitors, activators, and antioxidants.