Honeybush Extracts (Cyclopia spp.) Rescue Mitochondrial Functions and Bioenergetics against Oxidative Injury

Figure 1

(a–d) The water extracts of Cyclopia subternata, C. genistoides, and C. longifolia, and the 70% ethanolic extract of C. genistoides significantly increased the ATP levels up to 4%. The cells were treated for 24 h with the extracts. Values represent as the mean ± SEM of three independent experiments and were normalized on the untreated (CTRL) group (=100%). One-way ANOVA and post hoc Dunnett’s multiple comparison test versus CTRL cells.  < 0.05;  < 0.01;  < 0.001.

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