Research Article

Warfarin Accelerates Aortic Calcification by Upregulating Senescence-Associated Secretory Phenotype Maker Expression

Table 1

Baseline characteristics according to absence and presence of AC in patients from MESA.

AC, No AC, value

Demographics
Age (yr)<0.01
Gender, male (%)59450.03
Metabolic syndrome (%)40380.04
Hypertension (%)53480.02
Diabetes mellitus (%)34280.02
Body mass index (kg/m2)0.17
SASP
IL-6 (mg/dL)<0.01
TNF-α (mg/dL)<0.01
Biochemical index
Total homocysteine (μmol/L)<0.01
Glucose (mmol/L)0.03
Cholesterol (mmol/L)0.35
Serum creatinine (μmol/L)0.04
Vitamin K intake (μg)<0.01
Calcification score
Agatston score0<0.01

Data are presented as . values are from independent-sample -test, Mann-Whitney test, chi-squared test, and Fisher’s exact test for appropriate data between group AC and group no AC.