Inhibition of ERRα Aggravates Sepsis-Induced Acute Lung Injury in Rats via Provoking Inflammation and Oxidative Stress
Knockdown of ERRα accelerated LPS-induced inflammatory factor release in PMVECs. (a) Comparison of TNF-α and IL-1β levels in different groups at different time points. (b) Representative blots of ERRα, p65, p-p65, IKBα, and p-IKBα in the four groups (upper panel); quantitative results of ERRα, p65, p-p65, IKBα, and p-IKBα (lower panel). The values are expressed as .a compared with the Ctr and shERRα group; b compared with the LPS group.
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