Metformin Ameliorates Aβ Pathology by Insulin-Degrading Enzyme in a Transgenic Mouse Model of Alzheimer’s Disease

Figure 3

Metformin improves neurotrophic factors in APP/PS1 mice. The mRNA levels of (a) Syp, (b) Bdnf, and (c) Ngf in the APP/PS1 mice. Data represent the ( per group). , , and vs. WT; ^#, ^##, and ^### vs. APP/PS1.

(a)

(b)

(c)