Metformin Ameliorates Aβ Pathology by Insulin-Degrading Enzyme in a Transgenic Mouse Model of Alzheimer’s Disease

Figure 4

Metformin ameliorates oxidative stress and neuroinflammation in APP/PS1 mice. The level of (a) MDA and the activity of (b) SOD in the brain of APP/PS1 mice. The levels of (a) IL-1β and (b) IL-6 in the brain of APP/PS1 mice. Experimental values were expressed as the ( per group). , , and vs. WT; ^#, ^##, and ^### vs. APP/PS1.

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