Peroxiredoxin-1 Overexpression Attenuates Doxorubicin-Induced Cardiotoxicity by Inhibiting Oxidative Stress and Cardiomyocyte Apoptosis

Figure 2

Prdx1 overexpression protected against cardiac injury induced by DOX. (a) The protein levels of Prdx1 four weeks after AAV9-Prdx1 injection in mice (). (b, c) The results of body weight and HW/TL ratio measurements in mice (). (d–g) Biochemical determination of CK-MB and LDH levels in the heart and serum for the indicated groups (). (h) HE staining shows the pathological structure of the heart in mice (). compared with the NS group; ^# compared with the DOX group.

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