Calenduloside E Ameliorates Myocardial Ischemia-Reperfusion Injury through Regulation of AMPK and Mitochondrial OPA1

Figure 2

CE suppresses I/R-induced mitochondrial morphological damage and dysfunction. (a) Representative transmission electron microscopy (TEM) images of cardiac mitochondria. . . (b) Mean size of the mitochondria. (c) Myocardial ATP content. (d) Changes of mitochondrial permeability transition pore opening. (e) Cytochrome c oxidase activity. Data are presented as the (). ^# vs. sham; ^## vs. sham; vs. I/R; vs. I/R.

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